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GPAT Syllabus 2019 for pharmacy with Weightage Exam Pattern/Format PDF

GPAT Syllabus 2019

To crack Graduate Pharmacy Aptitude Test which is going to be conducted in the 3rd week of January 2019, candidate must need GPAT Syllabus 2019 for pharmacy!! So, here below we have provided Graduate Pharmacy Aptitude Test Syllabus along with Weightage Exam Pattern/Format PDF.

Aspirants who will appear for GPAT Exam may download updated GPAT Syllabus 2019 for pharmacy with paper pattern, weightage of marks. Pharmaceutics, Pharmaceutical Chemistry, Pharmacology and Pharmacognosy are the sections covered in GPAT Syllabus.

This page includes:

  • Graduate Pharmacy Aptitude Test syllabus
  • Process to get syllabus
  • Exam pattern

All India Council for Technical Education Institute conducts GPAT 2019 paper for offering admission in postgraduate pharmacy courses. Aspirants may score well in GPAT exam 2019 by going through topics as listed in GPAT Syllabus.

To get detailed GPAT Syllabus 2019 as well as GPAT exam pattern, read all information listed on below section of this page which is well created by the dedicated team members of

GPAT Syllabus

In order to prepare well for Graduate Pharmacy Aptitude Test, refer to latest topics added in GPAT exam Syllabus. Graduate Pharmacy Aptitude Test is a national level entrance exam organized for providing admission to Master’s program of Pharmacy (M.Pharm) course.

GPAT paper comprise of listed subjects

  • Physical Chemistry
  • Physical Pharmacy
  • Organic Chemistry
  • Pharmaceutical Chemistry
  • Pharmaceutics
  • Pharmacology
  • Pharmacognosy
  • Pharmaceutical Analysis
  • Biochemistry
  • Biotechnology
  • Microbiology
  • Pathophysiology
  • Biopharmaceutics and Pharmacokinetics
  • Clinical Pharmacy and Therapeutics
  • Anatomy
  • Physiology and Health Education
  • Pharmaceutical Engineering
  • Pharmaceutical Management
  • Dispensing and Hospital Pharmacy

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GPAT Syllabus 2019:

GPAT Syllabus for Physical Chemistry:

Topic Detailed description of topics added in GPAT Syllabus
Composition & physical states of matterIntermolecular forces & their impact on state of the matter. Various physical properties of matter, dipole moment, dielectric constant, Van Der waal’s equation & critical phenomenon, liquefaction of gases, aerosols
Colligative PropertiesThe liquid state, vapor pressure, ideal & real solutions. Raoult’s law, elevation of boiling point, depression of freezing point, osmotic pressure, determination of molecular weight based on colligative properties.
ThermodynamicsFirst, second & third law of thermodynamics. Thermochemical laws, isothermic & adiabetic processes, reversible processes, work of expansion, heat content, enthalpy, heat capacity. Gibb’s & Helmoltz equation & chemical potential.
Chemical Equillibria, Phase ruleOne, two, & three component systems along with their applications. Solid- solid, solid – liquid, & liquid-liquid systems. Distillation of binary systems, azeotropic mixtures, steam, vacuum, & fractional distillation.
Refractive indexRefractive index, specific refractivity, molar refractivity, refractometers.
SolutionsSolubility, factors affecting solubility, solubility curves. Types of solutions, effect of cosolvancy, pH & other factors on solubility. Solubility of gases in liquids, liquids in liquids, & solids in liquids, critical solution temperature, law of partitioning & its applications. Solute solvent interactions. Expression of concentration of pharmaceutical solutions & calculations. Molarity, molality, mole fraction & percentage expressions
ElectrochemistryProperties of electrolyte solutions, electrolysis. Faraday’s law of electrolysis, electron transport, electrical cell, single electrode potential, concentration cells, half-cells & half cell potential, types of half cells, sign convention, Nerst equation, salt bridge, electromotive series, standard potential, SHE. Measuring the relative voltage of half cells, Calculation of standard potential. Reference & indicator electrodes. Standard oxidation-reduction potential
Ionic equilibriumTheory of conductivity, equivalent conductance, mobility of ions, specific conductance.
KineticsOrder of reactions, derivation & internal form of rate laws, molarities of reaction, derivation of rate constants.

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GPAT 2019 syllabus For Physical Pharmacy:

Topic Detailed description of topics added in GPAT Syllabus
Matter, properties of matterStates of matter, change in the state of matter, latent heat and vapor pressure,sublimation-critical point, eutectic mixtures, gases, aerosols- inhalers, relative humidity, liquid complexes, liquid crystals, glasses state, solid crystalline and amorphous polymorphism
Micromeritics and powder rheologyParticle size and distribution, average particle size number and weight distribution, particle number, method of determining particle size and volume, optical microscopy, sieving, sedimentation, determining surface areas, permeability, adsorption, derived properties of powders, porosity, packing arrangement densities, bulkiness and flow properties.
Surface and interfacial phenomenonLiquid interface, surface and interfacial tensions, surface free energy, measurement of surface and interfacial tension, spreading coefficient, adsorption and liquid interfaces, surface active agents, HLB classification, solubilization, detergency, absorption at solid interfaces, solid gas and solid liquid interfaces, complex films, electrical properties ofinterfaces
Viscosity and rheologyNewtonian systems, law of flow, kinematics viscosity, effect of temperature, non Newtonian systems, pseudoplastics, dilatant, plastic, thixotropy in formulations, determination of viscosity and thixotropy by capillary, falling ball, rotational viscometer, application of theology in pharmacy
Dispersion systemsColloidal dispersions: Definition, types, properties of colloids, protective colloids, application of colloids in pharmacy, Suspensions and emulsions: Interfacial properties of suspended particles settling in suspension, theory of sedimentation, effect of Brownian movement, sedimentation of flocculated particles, sedimentation parameters, wetting of particles

Significance of electrical properties in dispersions, controlled flocculation, flocculation in structured vehicles, rheological considerations, emulsions: types, theories, physical stability

ComplexationClassification of complexes, methods of preparations and analysis, applications
BufferBuffer equations and buffer capacity in general. Buffers in pharmaceutical systems, 5 preparations and stability, buffered isotonic solutions. Measurements of tonicity calculations and methods of adjusting isotonicity
SolubilityMiscibility-influence of foreign substances  three component systems

dielectric constant and solubility

solubility of solids in liquids

ideal and non-ideal solutions, solvation and association in solutions

Solubility of salts in water, solubility of slightly soluble and weak electrolyte, calculating solubility of weak electrolytes as influenced by pH, influence of solvents on the solubility of drugs  combined effect of pH and solvents, distribution of solutes between immiscible

solvents, effect of ionic dissociation and molecular association on partition, extraction, preservative action of weak acids in emulsions, drug action and distribution co-efficient

Concepts of dissolution and diffusion

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GPAT Syllabus of Organic Chemistry:

General principles
Different classes of compounds
Protection & deprotection of groups
Aromaticity & aromatic chemistry
Polycyclic aromatic hydrocarbons
Carbonyl Chemistry
Different aromatic classes of compounds
Bridged rings
Heterocyclic Chemistry
Amino acids & proteins
Pericyclic reactions

 GPAT Syllabus of Pharmaceutical Chemistry:

Topic Topics added in GPAT Syllabus
Pharmaceutical Impurities
  • Impurities in pharmaceutical substances
  • Limit tests for heavy metals like lead, iron
  • Types & effects of impurities
  • Sources of Impurities
  • Monograph & its importance
  • Various tests included in monographs as per I. P. A study
  • Methods of preparation, assay, & pharmaceutical uses
  • Isotopes- stable & radioactive
  • Types & measurement of radioactivity
  • Mode & rate of decay
  • Radiopharmaceuticals & their diagnostic & therapeutic applications
  • Radiocontrast media, use of BaSO4 in medicine
Therapeutic classes of drugs
  • Stereochemical aspects
  • Dentifrices, desensitizing agents, & anticaris agents
  • Local anesthetics.
  • General anesthetics.
  • Purgatives, laxatives & antidiarrhoeal agents
  • Diagnostic agents.
  • Coagulants, anticoagulants & plasma expanders
  • Antiseptics, disinfectants, sterilants, & astringents.
Drug metabolismBased on the functional groups
Different classes of therapeutic drugs
  • Physicochemical properties
  • Synthesis of simple & prototype molecules
  • Neuroleptics
  • Anti-anxiety drugs.
  • Sedative-hypnotics
  • Antiepileptic agents
  • Antibiotics. Penicillins, cephalosporins & other beta- lactam antibiotics
  • Steroids. Corticosteroids [gluco- & mineralocorticoids] & anti-inflammatory steroids.
  • Drug resistance, wherever applicable
Various classes of therapeutic agents
  • Antiamoebic agents
  • Anthelmintic agents
  • Antibacterial sulpha drugs [only]
  • Quinolone antibacterials Antimycobacterial drugs
  • Antifungal agents
  • Antiviral agents including HIV & anti-HIV drugs
  • Thyroid & anti thyroid drugs
  •  Antiallergic agents
  •  Antiulcer agents & Proton Pump Inhibitors
  • Hypoglycemic agents
  •  Antimalerials
Different classes of therapeutic drug
  • Sedative-hypnotics
  • Antiepileptic agents
  • Neuroleptics.
  • Anti-anxiety drugs.
  • Diuretics, Steroids.
  • Antibiotics.
  • Penicillins, cephalosporins & other beta- lactam antibiotics

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GPAT Syllabus of Pharmaceutics:

Pharmacy Profession
Introduction to Pharmaceuticals
Introduction to dosage form
Route of administration
Sources of drug information
Allopathic dosage form
Crude extract
Allergenic extract
Ayurvedic system of medicine
Homeopathic system of medicine
Biological products
Packaging Materials
GMP and Validation
Pilot plant scale up techniques

GPAT Syllabus of Pharmacology:

General Pharmacology
  • Introduction to Pharmacology
  • Definition, scope and source of drugs
  • Pharmacodynamics-Mechanism of drug action
  • Pharmacokinetics-Mechanism and principle of Absorption
  • Distribution, Metabolism and Excretion of drugs
  • Discovery and development of new drugs
Pharmacology of cardiovascular system
  • Anti-hypertensive drugs
  • Introduction of hemodynamic and Electrophysiology of heart
  • Drugs used in congestive heart failure
  • Anti-hyperlipidemic drugs
  • Drugs used in the therapy of shock
  • Haematinics, anticoagulants and haemostatic agents
  • Fibrinolytics and antiplatelet drugs
  • Blood and plasma volume expander
Drugs acting on Respiratory system
  • Anti-asthmatic drugs
  • Mucolytics and nasal decongestants
  • Anti-tussives and expectorants
  • Respiratory stimulants
Pharmacology of central nervous System
  • Neurohumoral transmission in the C.N.S
  • Pharmacology of various neurotransmitters
  • General anesthetics
  • Alcohols and disulfiram
  • Sedatives, hypnotics and centrally acting muscle relaxants
  • Psychopharmacological agents
  • Antipsychotics, antidepressants, antianxiety agents
  • Anti-manics and hallucinogens
  • General Principles of chemotherapy
  • Sulphonamides and co-trimoxazole
  • Antibiotics- Penicillins
  • Cephalosporins, chloramphenicol, Macrolides, quinolines and fluoroquinolins
  • Chemotherapy of tuberculosis, leprosy, fungal diseases, viral diseases
  •  AIDS, protozoal diseases, worm infections
  • Chemotherapy of malignancy
Principles of toxicology
  • Definition of poison
  • General principles of treatment of Poisoning
  •  Treatment of poisoning due to Heavy metals, insecticides, opioids and other addict forming drugs
  • Study of acute, sub acute and chronic toxicity as per OECD guidelines
Peptides and proteins as mediators
  • General Principal of peptide pharmacology
  • Biosynthesis and regulation of peptides Peptide antagonists
  • Protein and peptide as drugs
Autacoids and their Antagonists
  • Histamine, 5-HT and their antagonists
  • Prostaglandins, thromboxanes and leukotrienes
  • Pentagastrin, cholecystokinin, angiotensin
  • Bradykinin and substance
  • P. Analgesic, anti-pyretic, anti-inflammatory
Pharmacology of Endocrine system
  • Basic concepts in endocrine pharmacology
  • Hypothalamic and pituitary hormones
  • Thyroid hormones and ant thyroid drugs
  • Parathormone, Calcitonin and vitamin-D. Insulin
  • Oral hypoglycemic agents and glucagon
  • ACTH and corticosteroids
  • Androgens and anabolic steroids.
  • Estrogens, progesterone and oral contraceptives
  • Drugs acting on the uterus

GPAT Syllabus of Pharmacognosy:

Introductory Pharmacognosy
Classification of crude drugs
Sources of crude drugs
Factors influencing quality of crude drugs
Techniques in microscopy
Introduction to phytoconstituents
Principles of plant classification
Traditional herbal drugs
Plants based industries and research institutes in India

Graduate Pharmacy Aptitude Test Syllabus for Pharmaceutical Analysis:

Importance Of Quality Control In Pharmacy
Non-Aqueous Titrations
Precipitation Titrations
Ultraviolet-Visible Spectrometry
Flame Photometry & Atomic Absorption Spectrometry
Proton Nuclear Magnetic Resonance Spectrometry
Acid-Base Titrations
Oxidation- Reduction Titrations
Complexometric Titrations
Extraction Techniques
Miscellaneous Methods Of Analysis
General Principles Of Spectroscopy
Infrared Spectrometry
Mass Spectrometry
Nephelometry & Turbidimetry

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GPAT Syllabus of Biochemistry:

Biological Oxidations & Reductions
Nucleic Acids
Hereditary Diseases

GPAT Syllabus of Biotechnology:

Plant Cell and Tissue Culture
Fermentation Technology and Industrial Microbiology
Process and Applications
Animal Cell Culture
Recombinant DNA Technology
Biotechnologv Derived Products
Formulation of Proteins and Peptides

GPAT Syllabus of Microbiology:

Introduction to Microbiology
Microscopy and staining technique
Biology of Microorganisms
Fungi and Viruses
Aseptic Technique
Sterilization & Disinfection
Microbial Spoilage
Immunology and Health
Vaccines & Sera
Microbial Assay

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GPAT Syllabus 2019 for Pathophysiology:

Basic Principles Of Cell Injury And Adaptation
Neoplastic Diseases
Biological Effects Of Radiation
Pathophvsiologv Of Common Diseases
Bio-Availability & Bio-Equivalence
Basic Mechanisms Of Inflammation And Repair
Auto-Immunity & Diseases Of Immunity
Protein Calorie Malnutrition, Vitamins, Obesity. Starvation
Infectious Diseases
Bio- Pharmaceutical Statistics

GPAT Syllabus for Anatomy, Physiology And Health Education:

Cell physiology
Gastrointestinal tract
Autonomic nervous system
Skeletal System
Urinary System
Reproductive System
Lymphatic system
Fluid flow
Dehumidification and humidity control
Material of constructions
Industrial hazards & safety precautions
The Blood
Respiratory System
Sense organs
Central Nervous system
Endocrine Glands
Cardio vascular system
Filtration and Centrifugation
Refrigeration and air conditioning
Automated process control systems
Heat transfer
Size reduction and size separation

GPAT 2019 Syllabus for Pharmaceutical Management:

Introduction to management
Inventory Management
Marketing Research
Human resource and development (HRD)
World trade organization (WTO) and trade related intellectual property rights (TRIPS)
Planning and Forecasting
Research Management
Leadership and motivation
Standard institutions and regulatory authorities

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GPAT Syllabus 2019 for Dispensing & Hospital Pharmacy:

Introduction to laboratory equipments, weighing methodology, handling of prescriptions, labeling instructions for dispensed products
Preparations based on maceration process.
Posological calculations involved in calculation of dosage for infants.
Preparations of formulations involving allegation, alcohol dilution, isotonic solution.
Compounding and dispensing of following prescriptions
Preparations based on percolation process.
Study of difference between marketed and dispensed products of different dosage forms.
Enlarging and reducing formula, displacement value.
Study of current patent and proprietary products, generic products and selected brand products, indications, contra indications, adverse drug reactions, available dosage forms and packing of ,
Reading and counseling of prescriptions from the clinical practice

GPAT Exam Pattern 2019

GPAT Exam Pattern:

  • There are total 125 questions in paper.
  • Time duration of test is of 180 minutes.
  • For each correct answer, you will get 4 marks.
  • There is a negative marking of 1 mark for wrong answer.
  • GPAT 2019 is of 500 marks.

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Process to avail GPAT 2019 syllabus PDF:

  • Log on to Official website of organization that is
  • Hit on “Syllabus” tab available at top menu bar.
  • GPAT Syllabus in PDF form will open up facing you.
  • Read out all topics as listed in GPAT Syllabus PDF.
  • Save GPAT  syllabus & prepare for exam as per topics prescribed in it.

GPAT 2019 Dates

EventsDates (Tentative)
Opening of registration portal3rd week of October 2018
Mock Test Available4th week of October 2018
Closing of registration4th week of December 2018
Releasing of admit card2nd week of January 2019
Exam date3rd week of January 2019
Objection TrackerTill 4th week of January 2019
Declaration of result2nd week of February 2019
All India Merit List3rd week of February 2019

Something you should know about GPAT 2019

Graduate Pharmacy Aptitude Test or you can say GPAT 2019 is conducted by All India Council for Technical Education to provide admission into the Master’s (M.Pharm) programmes. It is a national level entrance exam which scores is accepted by all AICTE-Approved Institutions/University Departments/Constituent Colleges/Affiliated Colleges.


For more details about GPAT Syllabus 2019, aspirants may follow its Official Link. Aspirants can join us on Facebook and Google Plus to gather more details in regard of GPAT Syllabus.

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