GPAT Syllabus

Graduate Pharmacy Aptitude Test (GPAT 2023) is national level entrance examination conducted by NTA for admission into M.Pharm programmes. The latest GPAT Syllabus 2023 contains Section Wise Details of chapters comprised in GPAT Entrance Exam 2023. Let’s discuss the Exam Pattern and topics covered in GPAT Exam Syllabus. You can also download the GPAT 2023 Syllabus in PDF format from here.

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Name of the Exam	Graduate Pharmacy Aptitude Test (GPAT)
Conducting Body	National Testing Agency (NTA)
Exam mode	Online
Exam duration	3 hours
Total questions	125
Maximum marks	500
Types of questions	Multiple choice questions (MCQs)
Marks per question	4 marks each question
Negative marking	One mark will be deducted from the total score for every wrong response.
Official Portal	gpat.nta.nic.in
The Helpline No	7042399521, 7042399525, 7042399526

GPAT Syllabus 2023

GPAT Exam Pattern

• The medium of Question Paper is English only.
• GPAT is an online computer-based test of 3 hours duration with 125 objective type questions.
• There are 4 marks for a correct answer.
• There shall be negative marking for wrong answers, for each wrong answer 1 mark shall be deducted.

From Here: GPAT 2023 Syllabus PDF Download

GPAT Exam Syllabus 2023

NTA GPAT Syllabus For Pharmacy

GPAT Syllabus for Physical Chemistry

Composition & Physical States Of Matter

Intermolecular forces & their impact on state of the matter. Various physical properties of matter, dipole moment, dielectric constant, Van Der waal’s equation & critical phenomenon, liquefaction of gases, aerosols

Colligative Properties

The liquid state, vapor pressure, ideal & real solutions. Raoult’s law, elevation of boiling point, depression of freezing point, osmotic pressure, determination of molecular weight based on colligative properties.

Thermodynamics

First, second & third law of thermodynamics. Thermochemical laws, isothermic & adiabetic processes, reversible processes, work of expansion, heat content, enthalpy, heat capacity. Gibb’s & Helmoltz equation & chemical potential.

Chemical Equillibria, Phase Rule

One, two, & three component systems along with their applications. Solid- solid, solid – liquid, & liquid-liquid systems. Distillation of binary systems, azeotropic mixtures, steam, vacuum, & fractional distillation.

Refractive index

Refractive index, specific refractivity, molar refractivity, refractometers.

Solutions

Solubility, factors affecting solubility, solubility curves. Types of solutions, effect of cosolvancy, pH & other factors on solubility. Solubility of gases in liquids, liquids in liquids, & solids in liquids, critical solution temperature, law of partitioning & its applications. Solute solvent interactions. Expression of concentration of pharmaceutical solutions & calculations. Molarity, molality, mole fraction & percentage expressions

Electrochemistry

Properties of electrolyte solutions, electrolysis. Faraday’s law of electrolysis, electron transport, electrical cell, single electrode potential, concentration cells, half-cells & half-cell potential, types of half cells, sign convention, Nerst equation, salt bridge, electromotive series, standard potential, SHE. Measuring the relative voltage of half cells, Calculation of standard potential. Reference & indicator electrodes. Standard oxidation-reduction potential

Ionic equilibrium

Theory of conductivity, equivalent conductance, mobility of ions, specific conductance.

Kinetics

Order of reactions, derivation & internal form of rate laws, molarities of reaction, derivation of rate constants.

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GPAT Syllabus For Physical Pharmacy

Matter, properties of matter

States of matter, change in the state of matter, latent heat and vapor pressure,sublimation-critical point, eutectic mixtures, gases, aerosols- inhalers, relative humidity, liquid complexes, liquid crystals, glasses state, solid crystalline and amorphous polymorphism

Micromeritics and powder rheology

Particle size and distribution, average particle size number and weight distribution, particle number, method of determining particle size and volume, optical microscopy, sieving, sedimentation, determining surface areas, permeability, adsorption, derived properties of powders, porosity, packing arrangement densities, bulkiness and flow properties.

Surface and interfacial phenomenon

Liquid interface, surface and interfacial tensions, surface free energy, measurement of surface and interfacial tension, spreading coefficient, adsorption and liquid interfaces, surface active agents, HLB classification, solubilization, detergency, absorption at solid interfaces, solid gas and solid liquid interfaces, complex films, electrical properties ofinterfaces

Viscosity and rheology

Newtonian systems, law of flow, kinematics viscosity, effect of temperature, non-Newtonian systems, pseudoplastics, dilatant, plastic, thixotropy in formulations, determination of viscosity and thixotropy by capillary, falling ball, rotational viscometer, application of theology in pharmacy

Dispersion systems

Colloidal Dispersions: Definition, types, properties of colloids, protective colloids, application of colloids in pharmacy

Suspensions And Emulsions: Interfacial properties of suspended particles settling in suspension, theory of sedimentation, effect of Brownian movement, sedimentation of flocculated particles, sedimentation parameters, wetting of particles Significance of electrical properties in dispersions, controlled flocculation, flocculation in structured vehicles, rheological considerations

Emulsions: Types, theories, physical stability

Complexation

Classification of complexes, methods of preparations and analysis, applications

Buffer

Buffer equations and buffer capacity in general. Buffers in pharmaceutical systems, 5 preparations and stability, buffered isotonic solutions. Measurements of tonicity calculations and methods of adjusting isotonicity

Solubility

Miscibility-influence of foreign substances three component systems dielectric constant and solubility solubility of solids in liquids ideal and non-ideal solutions, solvation and association in solutions Solubility of salts in water, solubility of slightly soluble and weak electrolyte, calculating solubility of weak electrolytes as influenced by pH, influence of solvents on the solubility of drugs combined effect of pH and solvents, distribution of solutes between immiscible solvents, effect of ionic dissociation and molecular association on partition, extraction, preservative action of weak acids in emulsions, drug action and distribution co-efficient Concepts of dissolution and diffusion

GPAT Syllabus of Organic Chemistry

• General Principles
• Different Classes Of Compounds
• Protection & Deprotection Of Groups
• Aromaticity & Aromatic Chemistry
• Polycyclic Aromatic Hydrocarbons
• Carbonyl Chemistry
• Different Aromatic Classes Of Compounds
• Bridged Rings
• Heterocyclic Chemistry
• Amino Acids & Proteins
• Pericyclic Reactions

GPAT Syllabus of Pharmaceutical Chemistry

Topic	Topics added in GPAT 2023 Syllabus PDF
Pharmaceutical Impurities	Impurities in pharmaceutical substances Limit tests for heavy metals like lead, iron Types & effects of impurities Sources of Impurities
Monographs	Monograph & its importance Various tests included in monographs as per I. P. A study Methods of preparation, assay, & pharmaceutical uses
Isotopes	Isotopes- stable & radioactive Types & measurement of radioactivity Mode & rate of decay Radiopharmaceuticals & their diagnostic & therapeutic applications Radiocontrast media, use of BaSO4 in medicine
Therapeutic classes of drugs	Stereochemical aspects Dentifrices, desensitizing agents, & anticaris agents Local anesthetics. General anesthetics. Purgatives, laxatives & antidiarrhoeal agents Diagnostic agents. Coagulants, anticoagulants & plasma expanders Antiseptics, disinfectants, sterilants, & astringents.
Drug metabolism	Based on the functional groups
Different classes of therapeutic drugs	Physicochemical properties Synthesis of simple & prototype molecules Neuroleptics Anti-anxiety drugs. Sedative-hypnotics Antiepileptic agents Antibiotics. Penicillins, cephalosporins & other beta- lactam antibiotics Steroids. Corticosteroids [gluco- & mineralocorticoids] & anti-inflammatory steroids. Drug resistance, wherever applicable
Various classes of therapeutic agents	Antiamoebic agents Anthelmintic agents Antibacterial sulpha drugs [only] Quinolone antibacterials Antimycobacterial drugs Antifungal agents Antiviral agents including HIV & anti-HIV drugs Thyroid & anti thyroid drugs Antiallergic agents Antiulcer agents & Proton Pump Inhibitors Hypoglycemic agents Antimalerials
Different classes of therapeutic drug	Sedative-hypnotics Antiepileptic agents Neuroleptics. Anti-anxiety drugs. Diuretics, Steroids. Antibiotics. Penicillins, cephalosporins & other beta- lactam antibiotics

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GPAT Syllabus of Pharmaceutics

• Pharmacy Profession
• Introduction To Pharmaceuticals
• Introduction To Dosage Form
• Route Of Administration
• Adme
• Sources Of Drug Information
• Allopathic Dosage Form
• Crude Extract
• Allergenic Extract
• Ayurvedic System Of Medicine
• Homeopathic System Of Medicine
• Biological Products
• Packaging Materials
• Gmp And Validation
• Pilot Plant Scale Up Techniques

GPAT Pharmacology Syllabus

Topic	Topics added in GPAT Syllabus 2023 PDF Download
General Pharmacology	Introduction to Pharmacology Definition, scope and source of drugs Pharmacodynamics-Mechanism of drug action Pharmacokinetics-Mechanism and principle of Absorption Distribution, Metabolism and Excretion of drugs Discovery and development of new drugs
Pharmacology of cardiovascular system	Anti-hypertensive drugs Introduction of hemodynamic and Electrophysiology of heart Drugs used in congestive heart failure Anti-hyperlipidemic drugs Drugs used in the therapy of shock Haematinics, anticoagulants and haemostatic agents Fibrinolytics and antiplatelet drugs Blood and plasma volume expander
Drugs acting on Respiratory system	Anti-asthmatic drugs Mucolytics and nasal decongestants Anti-tussives and expectorants Respiratory stimulants
Pharmacology of central nervous System	Neurohumoral transmission in the C.N.S Pharmacology of various neurotransmitters General anesthetics Alcohols and disulfiram Sedatives, hypnotics and centrally acting muscle relaxants Psychopharmacological agents Antipsychotics, antidepressants, antianxiety agents Anti-manics and hallucinogens
Chemotherapy	General Principles of chemotherapy Sulphonamides and co-trimoxazole Antibiotics- Penicillins Cephalosporins, chloramphenicol, Macrolides, quinolines and fluoroquinolins Chemotherapy of tuberculosis, leprosy, fungal diseases, viral diseases AIDS, protozoal diseases, worm infections Chemotherapy of malignancy
Principles of toxicology	Definition of poison General principles of treatment of Poisoning Treatment of poisoning due to Heavy metals, insecticides, opioids and other addict forming drugs Study of acute, sub-acute and chronic toxicity as per OECD guidelines
Peptides and proteins as mediators	General Principal of peptide pharmacology Biosynthesis and regulation of peptides Peptide antagonists Protein and peptide as drugs
Autacoids and their Antagonists	Histamine, 5-HT and their antagonists Prostaglandins, thromboxanes and leukotrienes Pentagastrin, cholecystokinin, angiotensin Bradykinin and substance P. Analgesic, anti-pyretic, anti-inflammatory
Pharmacology of Endocrine system	Basic concepts in endocrine pharmacology Hypothalamic and pituitary hormones Thyroid hormones and ant thyroid drugs Parathormone, Calcitonin and vitamin-D. Insulin Oral hypoglycemic agents and glucagon ACTH and corticosteroids Androgens and anabolic steroids. Estrogens, progesterone and oral contraceptives Drugs acting on the uterus

GPAT Syllabus of Pharmacognosy

Introductory Pharmacognosy	Classification of crude drugs
Sources of crude drugs	Factors influencing quality of crude drugs
Techniques in microscopy	Introduction to phytoconstituents
Principles of plant classification	Traditional herbal drugs
Plants based industries and research institutes in India	Patents

Graduate Pharmacy Aptitude Test Syllabus for Pharmaceutical Analysis

Importance Of Quality Control In Pharmacy	Non-Aqueous Titrations
Precipitation Titrations	Gravimetry
Potentiometry	Calibration
Ultraviolet-Visible Spectrometry	Flame Photometry & Atomic Absorption Spectrometry
Proton Nuclear Magnetic Resonance Spectrometry	Acid-Base Titrations
Oxidation- Reduction Titrations	Complexometric Titrations
Extraction Techniques	Miscellaneous Methods Of Analysis
General Principles Of Spectroscopy	Spectrofluorimetry
Infrared Spectrometry	Mass Spectrometry
Nephelometry & Turbidimetry	Miscellaneous
Polarography	Chromatography
Miscellaneous

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GPAT Exam Syllabus of Biochemistry

Cell	Proteins
Vitamins	Enzymes
Biological Oxidations & Reductions	Nucleic Acids
Carbohydrates	Lipids
Hereditary Diseases	—

GPAT Syllabus of Biotechnology

• Plant Cell and Tissue Culture
• Fermentation Technology and Industrial Microbiology
• Process and Applications
• Proteomics
• Animal Cell Culture
• Recombinant DNA Technology
• Biotechnologv Derived Products
• Formulation of Proteins and Peptides

GPAT 2023 Syllabus of Microbiology

Introduction Of Microbiology	Microscopy and staining technique
Biology of Microorganisms	Fungi and Viruses
Aseptic Technique	Sterilization & Disinfection
Microbial Spoilage	Immunology and Health
Vaccines & Sera	Microbial Assay

GPAT Syllabus 2023 for Pathophysiology

• Basic Principles Of Cell Injury And Adaptation
• Hypersensitivity
• Neoplastic Diseases
• Biological Effects Of Radiation
• Pathophvsiologv Of Common Diseases
• BIOPHARMACEUTICS AND PHARMACOKINETICS
• Bio-Availability & Bio-Equivalence
• Basic Mechanisms Of Inflammation And Repair
• Auto-Immunity & Diseases Of Immunity
• Shock
• Protein Calorie Malnutrition, Vitamins, Obesity. Starvation
• Infectious Diseases
• Bio-Pharmaceutics
• Bio- Pharmaceutical Statistics

GPAT Syllabus for Anatomy, Physiology And Health Education

Cell physiology	Gastrointestinal tract
Autonomic nervous system	Skeletal System
Urinary System	Reproductive System
Lymphatic system	Fluid flow
Evaporation	Drying
Extraction	Crystallization
Dehumidification and humidity control	Material of constructions
Industrial hazards & safety precautions	The Blood
Respiratory System	Sense organs
Central Nervous system	Endocrine Glands
Cardio vascular system	Pharmaceutical Engineering
Filtration and Centrifugation	Refrigeration and air conditioning
Automated process control systems	Heat transfer
Distillation	Size reduction and size separation
Mixing	—

GPAT Syllabus for Pharmaceutical Management:

• Introduction to management
• Organization
• Inventory Management
• Marketing Research
• Human resource and development (HRD)
• World trade organization (WTO) and trade related intellectual property rights (TRIPS)
• Planning and Forecasting
• Research Management
• Communication
• Leadership and motivation
• GATT
• Standard institutions and regulatory authorities

GPAT Subjects Syllabus 2023 for Dispensing & Hospital Pharmacy

• Introduction to laboratory equipment’s, weighing methodology, handling of prescriptions, labeling instructions for dispensed products
• Preparations based on maceration process.
• Posological calculations involved in calculation of dosage for infants.
• Preparations of formulations involving allegation, alcohol dilution, isotonic solution.
• Compounding and dispensing of following prescriptions
• Preparations based on percolation process.
• Study of difference between marketed and dispensed products of different dosage forms.
• Enlarging and reducing formula, displacement value.
• Study of current patent and proprietary products, generic products and selected brand products, indications, contra indications, adverse drug reactions, available dosage forms and packing of ,
• Reading and counseling of prescriptions from the clinical practice

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• GPAT By NTA
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Process of GPAT Syllabus PDF Download:

• Log on to Official website of organization that is ntagpat.nic.in
• Hit on “Syllabus” tab available at top menu bar.
• GPAT Course Syllabus in PDF form will open up facing you.
• Read out all topics as listed in GPAT Syllabus PDF.
• Save NTA GPAT Syllabus & prepare for exam as per topics prescribed in GPAT 2023 Syllabus.

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GPAT Score 2023

• The result of GPAT 2023 will be declared by 2nd week of February 2023 as GPAT Score which will be accepted by over 1000 participating institutes.
• The participating institutes of GPAT 2023 are the institutions which will be accepting the GPAT Score.
• Candidates must apply separately to each of the GPAT 2023 participating institutes with the GPAT Score 2023.
• Then, each participating institute will release their respective cut – off GPAT Score which candidates should meet to get qualified for admission to that particular institute.
• Candidates are advised to see the details of the admission process of each participating institute of GPAT 2023 on their respective website.

Graduate Pharmacy Aptitude Test

Graduate Pharmacy Aptitude Test (GPAT 2023) is conducted by National Testing Agency (NTA) from last year to provide admission into the Master’s (M. Pharm) programmes. It is a national level entrance exam which scores is accepted by all AICTE-Approved Institutions/ University Departments/ Constituent Colleges/Affiliated Colleges.

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